5-Bromo-2-Fluorobenzyl Alcohol

5-Bromo-2-Fluorobenzyl Alcohol - Names and Identifiers

Name	5-Bromo-2-fluorobenzylamine hydrochloride
Synonyms	HCl RARECHEM AL BD 0325 5-Bromo-2-Fluorobenzyl Alcohol 5-BROMO-2-FLUOROBENZYL ALCOHOL (5-BROMO-2-FLUOROPHENYL)METHANOL (5-bromo-2-fluorophenyl)methanol Benzenemethanol, 5-bromo-2-fluoro- 5-Bromo-2-fluorobenzylamine hydrochloride 1-(5-Bromo-2-fluorophenyl)methanamine hydrochloride
CAS	99725-13-0
InChI	InChI=1/C7H6BrFO/c8-6-1-2-7(9)5(3-6)4-10/h1-3,10H,4H2

5-Bromo-2-Fluorobenzyl Alcohol - Physico-chemical Properties

Molecular Formula	C7H6BrFO
Molar Mass	205.02
Density	1.658g/cm³
Melting Point	221-226°C(lit.)
Boling Point	261.6°C at 760 mmHg
Flash Point	112°C
Vapor Presure	0.00578mmHg at 25°C
Storage Condition	Sealed in dry,Room Temperature
Refractive Index	1.566

5-Bromo-2-Fluorobenzyl Alcohol - Risk and Safety

Hazard Symbols	Xi - Irritant
Risk Codes	36/37/38 - Irritating to eyes, respiratory system and skin.
Safety Description	S26 - In case of contact with eyes, rinse immediately with plenty of water and seek medical advice. S36 - Wear suitable protective clothing.
WGK Germany	3
Hazard Note	Irritant

5-Bromo-2-Fluorobenzyl Alcohol - Introduction

5-Bromo-2-fluorobenzylamine hydrochloride is an organic compound with the chemical formula C7H7BrFN · HCl. The following is a description of its nature, use, preparation and safety information:

Nature:
-Appearance: White crystalline solid.
-Melting point: about 160-162°C.
-Solubility: It is easy to dissolve in water and some organic solvents (such as ethanol and dimethyl sulfoxide).

Use:
-5-bromo-2-fluorobenzylamine hydrochloride can be used as an intermediate in organic synthesis.
-It is commonly used in drug research and development and is involved in the synthesis of biologically active compounds.

Preparation Method:
The preparation method of 5-bromo-2-fluorobenzylamine hydrochloride can be achieved by the following steps:
1.5-bromo -2-fluorobenzyl alcohol reacts with anhydrous hydrochloric acid to generate 5-bromo -2-fluorobenzyl hydrochloride.
2.5-bromo -2-fluorobenzyl hydrochloride is reacted with ammonia to generate 5-bromo -2-fluorobenzylamine hydrochloride.
3. Purify by crystallization to give the final product.

Safety Information:
The specific safety information for 5-bromo-2-fluorobenzylamine hydrochloride depends on the specific use and conditions. However, as a chemical substance, the following safety precautions are usually required:
-Avoid inhalation and skin contact. Personal protective equipment such as gloves, goggles and protective clothing should be used.
-Avoid ingestion. If swallowed, seek medical attention immediately.
-During use and storage, avoid contact with oxidants and strong acids.

In general, when using 5-bromo-2-fluorobenzylamine hydrochloride, the relevant laboratory safety guidelines should be followed, and appropriate protective measures should be taken to ensure personal safety and the safety of the laboratory environment.

Last Update：2024-04-09 21:32:44